Abstract NLRP3 induces caspase-1-dependent pyroptotic cell death to drive inflammation. Aberrant activity of NLRP3 occurs in many human diseases. NLRP3 activation induces ASC polymerization into a single. micron-scale perinuclear punctum. https://www.markbroyard.com/top-super-pet-naturals-busy-butter-calming-peanut-butter-for-cheap-limited-save/