Three related proteins of the plakophilin family (PKP1_3) have been identified as junctional proteins that are essential for the formation and stabilization of desmosomal cell contacts. Failure of PKP expression can have fatal effects on desmosomal adhesion. leading to abnormal tissue and organ development. Thus. https://www.chiggate.com/3m-speedglas-9002nc-welding-helmet-fashion/